defy medical spa

Age is Just a Number

We are pleased to offer a broad spectrum of treatments to our clients:
Semaglutide/Tirzepatide Injections
Botox /Fillers/ PDO lifting threads
Customized Facials/ Eye lash extensions
Microdermabrasion/Chemical Peels/Dermaplane
Laser Hair Removal
Venus legacy Skin Tightening/Body Sculpting
Pixel Pro RF Micro needling
Fractional CO2 laser resurfacing
Opus Plasma laser treatments

Available Products

pca skin logobotox logojuvederm logoopus plasma logo

Full Range of Services

dr gieseke
About dr. Gieseke

Board Certified Physician

Dr. Gieseke became interested in the field of aesthetics 20 years ago when many of her patients started exploring affordable, safe, non-surgical ways to look more youthful and refreshed.  After extensive training, she expanded her practice to offer cosmetic services, including Botox, Fillers, Chemical Peels, Microdermabrasion, IPL and multiple Laser skin treatments. She is also now offering PDO Lifting threads!!

In August 2013, to meet the growing demand for cosmetic services, Dr. Gieseke proudly opened Defy Medical Spa on Old South Gaylord Street. Defy Medical Spa provides a comfortable, serene setting where her clients can relax and just enjoy treating themselves to a variety of services. We are also proud to offer massage therapy through Enchanted Massage at our same location.

Dr. Lisa Gieseke

Get a Free Consultation

​​Inner Beauty is your job. We do the rest.


Great past results for our clients


Hear what our past clients say

What satisfied Defy Medical Spa clients are saying about their face & body treatments including Botox, Dermal Fillers, Laser treatments, and more.

schedule an appointment

“Dr. Gieseke provides personal cosmetic advise with never trying to pressure you. The new Viveve laser has made exercise so much more enjoyable and spontaneous. I can actually jump and run without making 2 trips to the bathroom. It tightens up all the pelvic floor muscles. An hour laser treatment beats doing daily kegels with minimal results. Dr. Gieseke makes you feel comfortable and at ease during the entire process. You won’t find a better doctor in all of Denver!“

testimonial client
natasha b.

"Amazing!!! I went in for laser hair removal of my underarms and the whole Brazilian area. Dr. Gieseke made this process as smooth and painless as possible. She started by getting to know my history, fully prepped me for what to expect in this session, future sessions and long term. Underarms took like 2 min total for both and Brazilian took maybe ten minutes total and mostly for prep. Soooo much better than the traditional waxes I've always done. She's hilarious and so so knowledgable! Thanks Dr. G!"

Roxy v.
Defy customer